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Updated: May 17, 2025

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments
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电荷在 IDP 和折叠域之间的动态无序复合体中的作用

Katrine Bugge1, Andrea Sottini2, Miloš T Ivanović2

  • 1REPIN and the Structural Biology and NMR Laboratory, The Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark. katbugge@gmail.com.

Nature communications
|April 4, 2025
PubMed
概括

一个折叠的蛋白质域可以与带电的内在无序蛋白质 (IDP) 结合,形成一个稳定的复合体,其中 IDP 仍然无序. 这种电荷驱动的相互作用显示出基于折叠域的电荷分布的选择性.

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