脂质积累产品与相对握力之间的关联:一项基于人口的大型研究
Qian Wu1,2, Yicheng Ling2, Guiqiang Yuan3
1Department of Orthopedic Surgery, Wuxi Ninth People's Hospital Affiliated to Soochow University, Jiangsu, China.
Scientific reports
|April 4, 2025
概括
在美国成年人中,较高的脂质积累产品 (LAP) 水平与较低的相对握力 (RHGS) 有关. 这种反向关系凸显了LAP作为肌肉力量下降的潜在指标.
科学领域:
- 老年学是一门学科.
- 代谢健康 代谢健康
- 身体组成分析 身体成分分析
背景情况:
- 人口老龄化面临越来越多的慢性疾病,需要研究身体成分对健康的影响.
- 手握强度 (HGS) 和相对HGS (RHGS) 是肌肉强度和代谢健康的关键指标.
- 脂质积累产品 (LAP) 反映了内脏脂肪积累,但其与RHGS的关系尚未探索.
研究的目的:
- 为了研究脂质积累产品 (LAP) 和相对握力 (RHGS) 之间的关系.
- 探索有关身体组成和肌肉力量的潜在公共卫生见解.
主要方法:
- 利用了来自2011-2014年国家健康和营养检查调查 (NHANES) 数据库的数据.
- 使用腰围和甘油三水平计算LAP;从HGS和BMI衍生的RHGS.
- 在3990名参与者中使用多变量线性回归,光滑拟合曲线和值效应分析.
主要成果:
- 在LAP和RHGS之间发现了显著的反相关性 (β = -0.0020,P < 0.0001).
- 非线性关系被确定为49.8083cm·mmol/L的断点.
- 这种关联在各种美国人群中保持一致.
结论:
- 增加LAP与RHGS相反相关,表明LAP的临床意义.
- LAP可以作为肌肉力量减少的预测指标,为早期干预策略提供信息.
- 这些发现有助于理解人体成分在代谢健康和衰老中的作用.
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