儿童类风湿性疾病中的炎症性肠病
Özen Taş1, Fatma Aydın1, Zarife Kuloğlu2
1Division of Pediatric Rheumatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey.
Clinical rheumatology
|April 4, 2025
概括
风湿性疾病 (RD) 像FMF,CNO和JIA可以与儿童的炎症性肠病 (IBD) 一起发生. 早期发现这种关联对于有效治疗和疾病管理至关重要.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 胃肠病学 胃肠病学
- 自免疫性疾病 自免疫性疾病
背景情况:
- 儿童类风湿病 (RD) 是一种全身性自身免疫/炎症性疾病.
- RD可能与炎症性肠病 (IBD) 相关,影响治疗疗效.
- 早期识别RD-IBD链接对于适当的患者管理至关重要.
研究的目的:
- 为了确定诊断为RD的儿科患者IBD的频率.
- 确定在患有RD的儿童中怀疑IBD的临床指标.
主要方法:
- 电子医疗记录的回顾性审查.
- 分析2012年至2024年间被诊断患有RD和IBD的患者.
- 专注于在儿科风湿病学科管理的患者.
主要成果:
- 在3%的家族地中海热 (FMF) 患者,7.5%的慢性非细菌性骨髓炎 (CNO) 患者和1.2%的青少年异常性关节炎 (JIA) 患者中诊断出IBD.
- 在被诊断为IBD的患者中,有一半患有克罗恩病 (CD);41.6%患有性结肠炎 (UC).
- 四名患者出现了不典型的症状,如贫血,体重减轻和生长迟缓,突出了诊断方面的挑战.
结论:
- RD,特别是FMF,JIA和CNO,可能与IBD有关.
- 儿童类风湿病学家应考虑在具有异常或非典型症状的RD患者中考虑IBD.
- 由于RD和IBD同时发生,因此需要仔细考虑疾病进展和治疗策略.
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