日常生活能力和睡眠在抑郁和认知功能中的调解作用基于结构方程模型
Liu Huijun1, Zhang Xiange2, Yang Ming2
1The First Clinical Medical College, Anhui Medical University, Hefei, 230032, China.
BMC geriatrics
|April 4, 2025
概括
老年人的抑郁症显著影响认知功能. 睡眠质量差和日常活动能力下降调解了这种关系,突出了维持老年认知的干预目标.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 老年人群中抑郁症和认知功能障碍的高发病率对社会构成重大负担.
- 新出现的证据将睡眠质量差和老年人日常活动受损与抑郁症和认知能力下降联系在一起.
- 了解这些关系对于开发支持健康衰老的干预措施至关重要.
研究的目的:
- 研究睡眠质量和日常活动能力在老年人抑郁症和认知功能之间的关系中扮演的调解角色.
- 为新的干预策略提供证据,旨在改善和延迟老年人认知衰退.
- 扩大目前关于老年人群认知健康多因素性质的研究.
主要方法:
- 利用了2019年安健康和预期寿命调查 (AHLS) 中的5470名参与者 (60岁以上) 的数据.
- 评估认知功能 (MMSE),抑郁症状 (PHQ-9),日常生活能力 (巴特尔指数) 和睡眠质量 (PSQI).
- 采用皮尔森相关性和结构方程建模来分析关系和调解效应.
主要成果:
- 观察到抑郁症症状对认知功能的显著直接负面影响 (β=-0.075).
- 抑郁症症状与睡眠质量差 (β=0.420) 和日常生活能力降低 (β=-0.161) 密切相关.
- 睡眠质量差和日常生活能力被发现调解了抑郁症和认知之间的关系 (两者的调解效应β=-0.020).
结论:
- 老年人的抑郁症症状与认知障碍有显著的关联.
- 睡眠质量差和日常生活能力下降是老年人抑郁症和认知功能之间的重要调解者.
- 未来的干预措施应侧重于改善老年人的心理健康,睡眠质量和日常活动参与度,以保持认知功能.
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