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系统性脊髓MRI与单独的大脑MRI的有限附加值,用于在随访期间将MS患者分类为活跃或不活跃

Jérémy Hong¹, Malo Gaubert^1,2, Mathilde Lefort³

¹Univ Rennes, CHU Rennes, Service de radiologie, 35000, Rennes, France.

Journal of neurology

|April 5, 2025

概括

系统性脊髓MRI很少需要用于多发性硬化症监测. 仅脑部MRI就足以跟踪疾病活动,即使存在脊髓病变.

科学领域:

神经学神经学
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

脊髓 (SC) MRI对于监测多发性硬化症 (MS) 疾病活动的必要性受到争论.
目前的多发性硬化症管理指南主要依赖于脑部MRI进行疾病监测.

研究的目的:

为了比较使用单独的大脑MRI检测疾病活动与联合大脑和SC MRI.
在MS患者中确定新的SC病变发展的预测因子.

主要方法:

在5年内对221名EMISEP队列 (68名患者) 的患者间隔进行了回顾性分析.
同时进行的大脑和SCMRI扫描进行了审查,以检测新的病变.
患者间隔被分类为有症状 (复发) 或无症状.

主要成果:

没有临床复发或脑MRI活动的SC MRI活动很少发生 (2%).
新的SC病变与基线脑病变数和间隔期间的新脑病变相关.
基线SC病变负载没有预测新的SC病变发生.

结论:

这些发现支持当前的指导方针,有利于单独使用脑部MRI进行常规的MS监测.
常规的SCMRI甚至对于具有显著的SC损伤负担的患者来说也可能不需要.

关键词:

疾病活动疾病活动纵向研究是一项纵向研究.这就是为什么MRI是MRI.多发性硬化症是多发性硬化症.脊髓是指脊髓中的一些部分.

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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...