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Updated: May 16, 2025

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基于结构相似性的搜索,寻找表现出对尿酸载体1的cis-和trans-抑制活性的glinides

Misa Sayama1, Takaaki Suzuki2, Yoshie Reien3

  • 1Division of Pharmacy, Chiba University Hospital, Chiba, Japan.

Molecular pharmacology
|April 5, 2025
PubMed
概括

某些药物,如glinides,通过抑制人体尿酸载体1 (URAT1) 来影响血清尿酸水平. 这种相互作用与它们的类似酸的化学结构有关,为药物副作用提供了洞察力.

关键词:
药物不良反应 药物不良反应结构活动关系 结构活动关系尿酸输送器是尿酸的输送器.

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