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Updated: May 16, 2025

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein
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Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein

Published on: June 30, 2019

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细胞EKT:一个强大的化学蛋白质工作流程,以描述细胞向激酶抑制剂的细胞向参与

Joel Rüegger1, Berend Gagestein2, Antonius P A Janssen1

  • 1Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, Einsteinweg 55, 2333 CC Leiden, The Netherlands.

Molecular & cellular proteomics : MCP
|April 5, 2025
PubMed
概括

这项研究介绍了CellEKT,这是一个新的化学蛋白质组学平台,用于测量药物向细胞中的作用. 细胞EKT有助于发现和开发更有选择性的激酶抑制剂,用于癌症等疾病.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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