红细胞输血在全身麻醉下的犬类和猫类患者
Hannah Brodie1, Charles T Talbot2, Andrew Foster3
1Department of Clinical Sciences and Services, Royal Veterinary College, University of London, Hatfield, UK.
Veterinary anaesthesia and analgesia
|April 5, 2025
概括
红细胞 (RBC) 输血在全身麻醉 (GA) 期间在狗和猫中显示,非临界患者的生存率有所改善. 危急病的动物 (ASA IV-V) 在GA之前开始输血红细胞时有更好的结果.
科学领域:
- 兽医麻醉学 兽医麻醉学
- 输血医学 输血医学
- 小动物内部医学 小动物内部医学
背景情况:
- 红细胞 (RBC) 输血是兽医学中的关键干预措施.
- 全身麻醉 (GA) 为需要输血的患者带来了独特的挑战.
- 了解GA期间输血结果对于临床决策至关重要.
研究的目的:
- 描述在GA期间接受红细胞输血的狗和猫的种群.
- 评估影响这些患者生存的因素.
- 为了确定RBC输血相对于GA启动的最佳时间.
主要方法:
- 在2016-2021年期间在GA期间接受红细胞输血的猫和狗的回顾性队列研究.
- 收集的数据包括信号,临床发现,GA的原因,输血细节,美国麻醉学会 (ASA) 状态和存活到出院的情况.
- 统计分析使用了沙皮罗-威尔克斯测试,皮尔森的千平方和威尔科森-曼-惠特尼U测试 (p <0.05).
主要成果:
- 88只动物 (18只猫,70只狗) 符合研究标准.
- 在GA期间输血的最常见原因是血液腹部管理.
- 在非临界动物 (ASA I-II) 中,生存率更高.
- 在GA (p < 0.001) 之前开始输血时,重病动物 (ASA IV-V) 的生存率有所改善 (p < 0.001).
- 输血量和开始时间没有显著影响整体存活率,除了ASA IV-V.
- 没有发现输血反应;整体存活率为79.5%.
结论:
- 在GA期间接受红细胞输血的非临界动物 (ASA I-II) 存活的可能性更高.
- 危急病的动物 (ASA IV-V) 在GA之前开始输血红细胞时显示出生存益处.
- 输血时间是一个关键因素,以改善GA接受的受损兽医患者的治疗结果.
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