沙特阿拉伯的耐药性:患病率,预测因素和治疗结果
Meshari Alghamdi1,2, Nedaa Alomari3,4, Aser F Alamri1,2
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences (KSAU), Riyadh, Saudi Arabia.
BMC neurology
|April 5, 2025
概括
抗药性 (DRE) 影响了沙特阿拉伯超过26%的患者,焦点是关键预测因素. 早期的DRE诊断和管理对于更好的结果至关重要.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 耐药性 (DRE) 是一个重大的全球健康挑战,影响了大量不响应常规治疗的患者.
- 关于沙特阿拉伯人口中DRE的流行率和特定风险因素的数据有限,需要有针对性的研究.
研究的目的:
- 为了估计沙特阿拉伯患者 (PWE) 中 DRE 的患病率.
- 在这个群体中描述DRE,并确定其发展的相关预测因素.
主要方法:
- 在2016年6月至2023年2月期间,在沙特阿拉伯利雅得的神经病诊所进行了一项涉及350名PWE的横截面研究,该研究涉及沙特阿拉伯利雅得的神经病诊所的350名PWE.
- 从医疗记录中提取数据,进行统计分析,包括描述性统计,皮尔森的千平方测试和多变量后勤回归来识别DRE预测因子.
- 一个p值<0.05被认为是统计学上显著的.
主要成果:
- 发现DRE的患病率为26.86% (350名患者中94名).
- 焦点发作类型被确定为DRE的主要预测因素 (AOR = 1.85,p = 0.03).
- 患有DRE的患者出现急诊的可能性更高,特定的抗发作药物 (瓦尔酸,卡巴马西平,拉莫) 与DRE状态有显著的关联.
结论:
- 沙特阿拉伯的DRE患病率与全球估计一致,突出显示其持续的重要性.
- 经常访问急诊室和使用抗发作药物多疗法,需要密切监测早期DRE诊断和改善患者的治疗结果.
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