20-54岁和55岁以上的中风负担的比较分析:基于2019年全球疾病负担研究
Zhuoxi Wang1,2, Yiqing Liu1, Rui Qie3
1Experimental Research Center, China Academy of Chinese Medical Sciences, 16 Dongzhimennei South Xiaojie, Dongcheng District, Beijing, China.
BMC public health
|April 5, 2025
概括
在年轻人 (20-54岁) 中,尤其是缺血性中风 (IS) 中,中风负担正在上升,而在老年人 (>55岁) 中正在下降. 高血压,BMI和血糖等危险因素在不同年龄组有不同的贡献.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 公共卫生 公共卫生
背景情况:
- 卒中是全球死亡和残疾的主要原因之一.
- 调查不同年龄人口的中风负担对于公共卫生战略至关重要.
研究的目的:
- 分析中风负担 (发病率,DALYs,死亡率,患病率) 的趋势,用于内出血 (ICH),下大脑下出血 (SAH) 和缺血性中风 (IS).
- 为了比较1990年至2019年的年轻成年人 (20-54岁) 和老年人 (>55岁) 之间的中风负担.
- 确定影响中风负担和健康不平等的流行病学因素.
主要方法:
- 利用的全球疾病负担研究2019年数据.
- 计算了特定年龄的发病率,DALY,死亡率和流行率.
- 雇佣的Joinpoint回归,分解分析和健康不平等分析.
主要成果:
- 在20-54岁的年龄组中,ICH和SAH的总体发病率下降,但IS的发病率增加.
- 在55岁以上的年龄组中,中风发病率显示出整体下降趋势.
- 与ICH和SAH相比,IS的死亡率和DALY减少较小,在55岁以上的群体中下降幅度更大.
- 所有类型的中风的发病率在20-54岁的群体中都增加,在55岁以上的群体中,IS的发病率略有增加.
- 脑卒中负担与区域发展有负相关性.
- 高静脉血压是常见的危险因素;高的BMI更多地影响了年轻人,而不正常的禁食血糖更多地影响了老年人.
结论:
- 20-54岁年龄组中风负担是一个日益严重的全球健康问题.
- 在经济发展较低的地区,缺血性中风的发生率尤其令人担忧.
- 需要有针对性的公共卫生干预措施来解决特定年龄的中风风险和差异.
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