抗炎饮食指数和细胞癌的风险
Tahir Taj1, Pernilla Sundqvist2, Alicja Wolk3
1Clinical Epidemiology and Biostatistics, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden. tahir.taj@oru.se.
British journal of cancer
|April 5, 2025
概括
坚持富含水果和蔬菜的抗炎饮食可能会降低细胞癌 (RCC) 的风险. 这种保护作用在女性中尤为显著,这表明饮食对预防癌有重大影响.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 饮食模式,包括水果,蔬菜,咖啡和茶的摄入量,以及有限的红肉和适度的酒精消费,与降低细胞癌 (RCC) 风险有关.
- 假设某些食物的抗炎性质是影响癌症发展的关键机制.
- 这项研究研究了坚持抗炎饮食和患RCC的风险之间的关系.
研究的目的:
- 评估抗炎饮食与细胞癌 (RCC) 风险之间的关联.
- 评估饮食模式在癌症预防策略中的潜力.
- 探索饮食-RCC风险关系中的性别特异性差异.
主要方法:
- 利用了来自瑞典两个大型队列的数据:瑞典乳房学队列和瑞典男性队列.
- 用96项食物频率问卷来评估饮食习惯.
- 抗炎饮食指数 (AIDI) 根据16个食物组计算;使用Cox比例危险模型识别和分析RCC病例.
主要成果:
- 总共71,421名参与者被跟踪了19.7年,在此期间诊断出431例RCC病例.
- 较高的抗炎饮食指数 (AIDI) 评分与RCC风险降低显著相关 (Q4对Q1:0.68的HR).
- 抗炎饮食和RCC风险之间的反向关联在女性 (HR:0.47) 与男性 (HR:0.83) 相比更为明显.
结论:
- 坚持抗炎饮食似乎与较低的细胞癌 (RCC) 风险有关.
- 抗炎饮食对RCC的保护作用在女性中尤为明显.
- 这些发现支持饮食干预措施在癌预防工作中的作用.
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