儿童社区获得性肺炎的低血症与细菌病因和严重性标志物有关
Adey Matani1, Nechama Sharon1, Niv Reiss2
1Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel.
低血症 (低) 在患有肺炎的住院儿童中很常见. 这种情况与细菌感染和较高的炎症标志物有关,表明疾病的严重程度.
科学领域:
- 儿科医院医学 儿科医院医学
- 传染性疾病 传染性疾病
- 儿科重症监护 儿科重症监护 儿科重症监护
背景情况:
- 低血症经常在住院儿童中观察到,特别是那些患有社区性肺炎的儿童.
- 虽然低血症的严重程度与疾病相关,但与特定传染病原体相关的数据仍然有限且不一致.
研究的目的:
- 在儿科肺炎患者中研究血清水平,疾病严重程度和致病原体之间的关系.
- 为了确定低血症是否与特定类型的肺炎和炎症标志物有关.
主要方法:
- 在2018年1月至2020年12月期间,对751名18岁以下儿童进行了回顾性分析,这些儿童因肺炎住院治疗.
- 摄入的水平与可能的病因病原体,临床参数和炎症标志物的比较.
主要成果:
- 低血症 (<135mEq/L) 在26%的儿童中存在,严重的低血症 (<130mEq/L) 在1%的儿童中存在.
- 含量<130mEq/L在疑似细菌性肺炎 (3%) 与病毒性 (0.6%) 或非典型细菌性感染相比显著更常见.
- 低血与较高的细菌感染几率相关 (OR为<135mEq/L的3.1,OR为<130mEq/L的6.8) 并与白细胞计数和C反应蛋白水平的升高相反相关.
结论:
- 低血是患有肺炎住院儿童的常见发现.
- 低血症的存在与炎症标志物升高和疑似细菌性肺炎的可能性更高有关.
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