使用简化的eSOFA评估的术后器官功能障碍与死亡率有关:单中心回顾性队列研究
Miho Hamada1, Toshiyuki Mizota2, Akiko Hirotsu1
1Department of Anesthesia, Kyoto University Hospital, 54 Shogoin-Kawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Journal of anesthesia
|April 6, 2025
概括
通过eSOFA测量的术后器官功能障碍与非心脏手术后90天死亡风险更高有关. 这种简化的eSOFA工具有助于预测患者的结果.
科学领域:
- 麻醉学和外科手术期间的医学.
- 关键护理医学 关键护理医学
- 手术结果研究研究.
背景情况:
- 术后器官功能障碍是非心脏手术后的一个重大问题.
- 准确评估器官功能障碍对于预测患者死亡率至关重要.
- 现有的评分系统在某些外科患者群体中可能存在局限性.
研究的目的:
- 通过简化的eSOFA评分来评估术后器官功能障碍与90天死亡率之间的关联.
- 评估eSOFA在预测非心脏手术后死亡率方面的有用性.
- 为了比较eSOFA的预测性能与SOFA和APACHE II等既有得分.
主要方法:
- 对24558名接受非心脏手术的成年患者 (2009-2019) 的回顾性分析.
- 主要暴露:在2天内使用eSOFA的术后器官功能障碍 (阳性eSOFA).
- 主要结局:90天死亡率,使用多变量考克斯回归和C-统计分析,用于预测ICU患者的预测性表现.
主要成果:
- 7.5%的患者出现了阳性eSOFA,90天死亡率为0.9%.
- 阳性eSOFA独立地与90天死亡率增加3倍的风险相关 (aHR:3.03).
- 越来越多的eSOFA阳性项目与更高的死亡风险相关;在ICU患者中,预测性表现与SOFA和APACHE II相比.
结论:
- 在2天内通过eSOFA发现的术后器官功能障碍是非心脏手术中90天死亡率的独立预测因素.
- eSOFA评分为评估这些患者的风险提供了一种有价值和简化的方法.
- 进一步的研究可能会探索将eSOFA整合到常规临床实践中,以加强患者监测.
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