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Updated: May 16, 2025

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发现了新的四基诺林衍生物作为强效,选择性和口服可用的AR抗剂

Leer Yuan1, Jianing Liao1, Yiyang Qin1

  • 1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

European journal of medicinal chemistry
|April 6, 2025
PubMed
概括

研究人员优化了四基诺林衍生物AT2成为一种强大的雄激素受体 (AR) 抗剂C2. 这种新的C2化合物在前列腺癌 (PCa) 治疗中表现有前途,因为其有效性和改善的药理动力学特性.

关键词:
受体对抗剂 受体对抗剂分子对接是分子对接.前列腺癌是什么意思 前列腺癌是什么意思结构与活动的关系.

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