在人类羊水样本中同时确定多种内分泌干扰化学物质,采用固相提取与液体染色体双重质谱法 (LC-MS/MS) 结合的方法

Lei Zhao1, Zi Lin2, Duan Ju3

  • 1School of Disaster and Emergency Medicine, Tianjin University, Tianjin, 300072, China; The First School of Medicine, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China; Wenzhou Safety (Emergency) Institute, Tianjin University, Wenzhou, 325000, Zhejiang, China.

Talanta
|April 6, 2025
PubMed
概括

一种新方法准确地测量了羊水中的59种产前内分泌干扰化学物质 (EDC). 这种分析有助于了解胎儿暴露于环境污染物的风险,例如双和PFAS.

相关概念视频

Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...