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含有内部标准的双电磁增强柔性核心外纳米粒子的无标签表面增强拉曼散射定量分析
Qijia Zhang1, Xiaodi Ma1, Peng Song2
1College of Chemistry, Liaoning University, Shenyang 110036, China.
Food chemistry
|April 6, 2025
概括
使用普鲁士蓝 (PB) 和银 (Ag) 纳米颗粒进行自我校准的新型灵活SERS基板提高了农药检测的灵敏度和准确性. 这一进步改善了对提拉姆和 thiabendazole 检测的定量分析.
科学领域:
- 纳米材料科学 科学 纳米材料科学
- 分析化学 分析化学
- 频谱学是一种光谱学.
背景情况:
- 传统的表面增强拉曼散射 (SERS) 基板往往缺乏自我校准,导致测量的高变化.
- 一些SERS基质的"咖啡环"效应和不均性阻碍了准确的定量分析.
- 开发强大而敏感的SERS基质对于检测农药等微量分析剂至关重要.
研究的目的:
- 设计和合成具有集成自校准功能的灵活SERS基板.
- 为了提高农药检测的灵敏度和准确性,使用新型SERS基板.
- 解决传统SERS基质的局限性,包括可变性和"咖啡环"效应.
主要方法:
- 制造一个灵活的Au@PB@Ag NPs-CFs SERS基板,封装一个普鲁士蓝 (PB) 层.
- 利用银外内的局部表面等离子体共振进行双重电磁增强.
- 测试基质的自我校准能力,灵敏度和农药 (胺,胺) 的定量检测通过直接擦拭.
主要成果:
- 自校准功能显著降低了相对标准偏差,从30.34%降至11.24%.
- 实现了检测提拉姆 (检测限值0.015μM) 和 thiabendazole (检测限值0.098μM) 的高灵敏度.
- 证明有效地减轻了"咖啡环"效应,并且由于基质的灵活性和均性,实现了高峰回收率 (81%116.6%).
结论:
- 开发的Au@PB@Ag NPs-CFs SERS基底提供了一个可靠而敏感的平台,用于自校准的农药检测.
- 基板的设计克服了SERS分析中的关键挑战,使准确的定量测量成为可能.
- 这种灵活的SERS基板具有在现场快速检测农业污染物的巨大潜力.
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