怀孕期间的亲密伴侣暴力和婴儿早期发育:一个潜在的出生队列研究
Nan Jiang1, Shuang-Shuang Ma2, Ping Zu1
1Department of Maternal, Child & Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China; MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, China; Anhui Provincial Key Laboratory of Environment and Population health across the Life Course, Anhui Medical University, Hefei, China; Center for Big Data and Population Health of IHM, School of Public Health, Anhui Medical University, Hefei, China.
Biological psychiatry
|April 6, 2025
概括
怀孕期间的亲密伴侣暴力 (IPV),特别是心理暴力,与婴儿神经发育迟缓有关. 带血炎可能是一个关键的生物学因素,将IPV与这些延迟联系起来.
科学领域:
- 围产期心理健康问题
- 儿童的神经发育 儿童的神经发育
- 生殖健康 生殖健康
背景情况:
- 怀孕期间的亲密伴侣暴力 (IPV) 与母亲和婴儿的不良结果有关.
- 关于IPV对婴儿早期神经发育的影响的研究有限.
- 将IPV与神经发育问题联系起来的生物机制尚不清楚.
研究的目的:
- 调查怀孕期间IPV与婴儿神经发育迟缓之间的关联.
- 探索产前和产后抑郁症和炎症标志物在这种关系中的作用.
- 确定潜在的生物学途径,介导IPV对婴儿神经发育的影响.
主要方法:
- 一项前性出生队列研究,从2018年3月到2023年7月,涉及3007对母婴对.
- 数据收集包括IPV,抑郁症,带血炎症指数,以及年龄和阶段问卷-3 (ASQ-3) 分数.
- 用多重逻辑回归分析来评估IPV与神经发育迟缓之间的关系.
主要成果:
- 9.8%的孕妇报告IPV,其中8.7%经历了心理暴力.
- 心理暴力显著增加了沟通,解决问题和个人-社会领域 (ASQ-3) 的延迟风险.
- 联合IPV和抑郁症加剧了神经发育风险;带血炎症介导了IPV,产前抑郁症和ASQ-3失败之间的关联的19.6%.
结论:
- 怀孕期间的心理暴力会对后代的神经发育产生负面影响.
- 心理压力的强度是观察到的神经发育延迟的一个关键因素.
- 带血炎症代表了一种潜在的生物学机制,将心理暴力与婴儿神经发育迟缓联系起来.
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