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Updated: May 16, 2025

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与膜相关的CH型环状指2通过向脂肪酸合成酶来防止与代谢功能障碍相关的脂肪肝疾病

Dongsheng Ni1, Zhaolai Qi1, Shuang Ma1

  • 1The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, 100730, PR China; Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, PR China.

Molecular metabolism
|April 6, 2025
PubMed
概括

膜相关的CH型环状指2 (MARCH2) 自主ubiquitination调节了代谢功能障碍相关的脂肪性肝病 (MAFLD) 中的肝脂稳态. 针对MARCH2脂肪酸合成酶 (FASN) 途径为MAFLD提供了一个有前途的治疗策略.

关键词:
这就是FASN.脂质代谢 脂质的代谢马夫尔德 (MAFLD) 是一个3月2日 - - 这是三月二日.在Ubiquitination中使用.

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