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Updated: May 16, 2025

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms
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沃尔夫拉姆综合征2基因 (CISD2) 缺陷破坏了β细胞中Ca2+介导的胰岛素分泌

Zhao-Qing Shen1, Wen-Tai Chiu2, Cheng-Heng Kao3

  • 1Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.

Molecular metabolism
|April 6, 2025
PubMed
概括

在沃尔夫拉姆综合征2 (WFS2) 糖尿病中,CISD2蛋白对β细胞功能和胰岛素分泌至关重要. 它的缺乏会损害葡萄糖平衡和β细胞的身份,提供治疗点.

关键词:
在CISD2的基础上,CISD2是CISD2.卡2+) 恒常状态糖尿病 糖尿病 糖尿病线粒体功能 线粒体功能沃尔夫拉姆综合症 2 沃尔夫拉姆综合症 2

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