来自Staphylococcus aureus的多药耐药性菌株的蒂米丁激酶的晶体结构

相关实验视频

Updated: Jun 22, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

9.1K

Anam Ashraf1, Ravi Kant Pal2, Md Imtaiyaz Hassan1

  • 1Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.

Biochimica et biophysica acta. Proteins and proteomics
|April 6, 2025
PubMed
概括

确定 Staphylococcus aureus 乙胺基因酶 (Sa-TK) 的晶体结构,揭示了其与人类 TK 的相似性. 这种结构洞察力有助于设计针对性抗菌剂来对抗黄金色杆菌感染.

关键词:
抗微生物治疗药物 抗微生物治疗药物药物目标是药物目标.它具有多种药物耐药性.黄金葡萄球菌黄金葡萄球菌提米丁酶酶的使用方法

更多相关视频

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep105011:27

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

3.9K
PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase09:31

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase

Published on: September 26, 2020

4.3K

相关概念视频

Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and acquisition...