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影响含有正酸盐颗粒的树脂基材料离子释放的变量
Filipe Teles Ximenes Mesquita1, Handially Dos Santos Vilela1, Rafael Bergamo Trinca1
1University of São Paulo School of Dentistry, Department of Biomaterials and Oral Biology, Av. Prof. Lineu Prestes, 2227, São Paulo, SP 05508-000, Brazil.
概括
从树脂基材料中释放的离子 (Ca2+) 受实验条件的显著影响. 频繁的浸泡介质更新,更大的介质体积和更高的样本表面面积与体积比率可以增强Ca2+的释放.
科学领域:
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
- 牙科材料科学 牙科材料科学
背景情况:
- 基于树脂的牙科材料被广泛使用.
- 酸二水合物 (DCPD) 的整合旨在改善材料的性能.
- 了解离子释放对于临床性能和安全至关重要.
研究的目的:
- 研究实验变量如何影响离子 (Ca2+) 从含有 DCPD 颗粒的树脂基材料中释放出来.
- 分析沉浸介质更新频率,体积和样品尺寸对Ca2+释放动学的影响.
主要方法:
- 使用 BisGMA 和 TEGDMA 制备了具有不同 DCPD 度 (25% 和 50%) 的树脂基材料.
- 在不同的实验条件下,使用ICP-OES量化了Ca2+释放.
- 使用Peppas-Sahlin方程建模释放动力学,通过ANOVA分析数据.
主要成果:
- 随着每周/两周一次的脱离离子水 (DW) 更新,与不太频繁的更新相比,观察到Ca2+释放的增加.
- 较高的DW体积和面积与体积比较大的标本导致Ca2+释放量显著增加.
- 扩散占25%的DCPD的早期释放,而聚合物放松随着时间的推移变得越来越显著,特别是在50%的DCPD.
结论:
- 沉浸介质更新频率,体积和样品尺寸等实验变量对含有DCPD的树脂材料释放的Ca2+离子产生了重大影响.
- 研究人员和临床医生在设计实验和解释与离子释放相关的结果时必须考虑这些因素.
- 了解这些变量对于预测材料行为和临床结果至关重要.
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