在健康的儿童和青少年的尿道流量测量严重下降
Li Yi Lim1, Stephen Shei-Dei Yang2
1Division of Urology, Department of Surgery, Taipei Tzu Chi Hospital, 289, Jianguo Road, Xindian District, New Taipei City, 231 Taiwan; Unit of Urology, Department of Surgery, Hospital Canselor Tuanku Muhriz, Jalan Yaacob Latif, Bandar Tun Razak, Wilayah Persekutuan Kuala Lumpur, 56000 Kuala Lumpur, Malaysia.
Journal of pediatric urology
|April 6, 2025
概括
在健康个体的尿流量测试中,深度滴 (DDs) 是常见的,但多重DDs是罕见的. 该研究提出了DDs的新标准,以改善下泌尿道功能障碍 (LUTD) 的诊断.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 儿科泌尿外科 儿科泌尿外科
- 尿动力学 尿动力学 尿动力学
背景情况:
- 尿流量测量对于诊断下尿路功能障碍 (LUTD) 至关重要.
- 目前对尿液流量计模式的定义,如停滞式,缺乏一致性,导致观察者之间的可靠性较低.
- 以前被认为表明功能障碍的特征,如"深度下降" (DDs),即使在健康个体中也被观察到.
研究的目的:
- 建立精确的标准来定义尿液流量计中的"深度下降" (DD).
- 在健康儿童和青少年的尿液流量测试中确定DDs的频率.
- 在不同观察者之间评估新的DD定义的可靠性.
主要方法:
- 定义DD为≥√Qmax的突然流量减少,其次是≥2毫升/秒的反弹.
- 分析了来自1787名5-18岁健康参与者的3158个尿液流量测量测量结果.
- 不包括使用文物 (n=466) 和低空体积 (n=1425) 的测试.
主要成果:
- 在1267个有效的尿液流量计曲线中,16.0%,7.4%和7.3%分别显示一个,两个或≥3个DD.
- 随着膀估计容量的增加,DD的发病率从26.1%的50-75毫升增加到51.2%,>150%的EBC.
- 除了大量空置量,DD发病率降至15.7% (一个DD),6.7% (两个DD) 和5.2% (≥三个DD).
结论:
- 在健康受试者的尿流量测试中,深度滴 (DDs) 是常见的,但多个DDs (≥2) 是不常见的.
- 存在≥2DDs,特别是如果复发,可能表明需要进一步评估下尿路功能障碍 (LUTD).
- 需要进一步的研究来验证DD定义及其与尿动力学发现的相关性,以定义停滞模式.
相关概念视频
01:22Ureters
260
The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
260
01:23Urinary Bladder
257
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
257
01:24Physiology of Urine Formation
2.4K
Urine formation is an essential function of the human body. It plays a critical role in maintaining homeostasis by regulating the volume and composition of body fluids. The kidneys, the primary organs involved in this process, filter blood to remove waste products and excess substances, ultimately producing urine.
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
2.4K