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相关概念视频

Urinary Bladder01:23

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...

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相关实验视频

Updated: Jun 23, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

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[对于膀癌的膀保护疗法]

Hajime Tanaka1, Yasuhisa Fujii

  • 1Dept. of Urology, Institute of Science Tokyo.

Gan to kagaku ryoho. Cancer & chemotherapy
|April 7, 2025
PubMed
概括

膀癌的治疗方法因阶段而异. 新型膀保护疗法正在出现,用于对Bacillus Calmette-Guérin (BCG) 无反应的非肌肉侵入性膀癌 (NMIBC) 和肌肉侵入性膀癌 (MIBC),当激进囊切除术不是一种选择时.

科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 在瘤学瘤学.

背景情况:

  • 膀癌被分为非肌肉侵入性 (NMIBC) 和肌肉侵入性 (MIBC) 类型.
  • NMIBC治疗包括通过尿道切除和静脉内疗法,用于高风险病例的Bacillus Calmette-Guérin (BCG).
  • 肌肉侵入性膀癌 (MIBC) 的标准治疗方法是激进囊切除术,但对于不符合条件的患者,需要选择其他方法.

研究的目的:

  • 审查当前和新兴的膀癌治疗策略.
  • 为了突出 NMIBC 和 MIBC 膀保护方面的进展.
  • 确定患者选择和治疗标准化新疗法的挑战.

主要方法:

  • 对NMIBC和MIBC当前临床实践的审查.
  • 对新出现的膀保护策略的分析,包括MIBC的三模式治疗.
  • 讨论BCG不响应NMIBC的治疗反应和挑战.

主要成果:

  • 膀瘤通过尿道切除 (TURBT) 和静脉内疗法是NMIBC的标准.
  • 细菌卡尔梅特-盖林 (BCG) 疗法是有效的,但一些NMIBC病例成为BCG不响应.
  • 激进囊切除术是MIBC的标准,但正在为特定患者开发膀保护疗法.

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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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结论:

  • 新的治疗方法旨在在BCG不响应的NMIBC中保存膀.
  • 多模式膀保护疗法,像三模式疗法一样,为MIBC患者提供了选择.
  • 优化患者选择和标准化方案对于膀保护策略的成功至关重要.