过敏性鼻炎的鼻内针治疗:随机对照试验的系统审查和元分析
Xiao-Ying Chen1,2, Qian-Yun Wang1,3, Zhan-Feng Yan4,5
1Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Integrative medicine research
|April 7, 2025
概括
鼻内针疗法 (IAT) 在减少过敏性鼻炎症状和改善生活质量方面表现有前途. 然而,需要更严格的试验来确认其安全性和有效性.
科学领域:
- 综合医学是一个整体医学.
- 过敏和免疫学 过敏和免疫学
- 传统中国医药 传统中国医药
背景情况:
- 过敏性鼻炎 (AR) 是一种影响鼻腔通道的常见疾病.
- 鼻内针疗法 (IAT) 是一种新兴的AR治疗方法.
- 本研究评估了IAT对AR管理的有效性和安全性.
研究的目的:
- 评估鼻内针治疗 (IAT) 在治疗过敏性鼻炎 (AR) 的有效性.
- 评估IAT作为AR治疗的安全性概况.
- 综合来自随机对照试验 (RCT) 对AR的IAT的证据.
主要方法:
- 在9个数据库中进行系统的文献搜索,截至2024年9月.
- 包括涉及AR患者接受IAT (单独或作为附加剂) 的RCT.
- 使用Cochrane偏差风险2.0和GRADE进行质量评估;使用RevMan 5.4.1.1.进行的元分析.
主要成果:
- 分析了1889名参与者的21个RCT.
- 与假相比,IAT显著降低了总鼻腔症状得分 (中度证据).
- 与抗组胺药物相比,IAT改善了生活质量和减少了非症状得分 (中度证据);没有报告严重不良事件.
结论:
- IAT可以为AR症状和生活质量提供好处.
- 由于报告的限制,IAT的安全性需要进一步调查.
- 高质量,精心设计的试验是必要的,以确定关于AR的IAT的最终结论.
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