患者报告的结果衡量良性食道疾病的结果
John E Pandolfino1, Ronnie Fass2, Walter W Chan3
1Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
The American journal of gastroenterology
|April 7, 2025
概括
患者报告结果 (PRO) 措施对于评估患者健康至关重要. 目前对良性食道疾病的PRO如GERD,EoE和achalasia是有限的,需要改进的工具来进行全面的评估.
科学领域:
- 胃肠病学和患者报告的结果
- 临床评估工具 临床评估工具
- 消化道疾病管理管理
背景情况:
- 患者报告结果 (PRO) 措施对于评估患者在健康和疾病方面的主观体验至关重要.
- 对于食道疾病的现有PRO,包括胃食道逆流症 (GERD),eosinophilic esophagitis (EoE) 和achalasia,通常在范围或心理特征上是有限的.
- 需要全面的,用户友好的PRO,以捕捉良性食道疾病中全方位的症状和疾病状态.
研究的目的:
- 突出目前良性食道疾病患者报告结果措施的局限性.
- 确定对GERD,EoE和achalasia进行改进和全面的PRO工具的需求.
- 强调评估食道过敏和焦虑在患者结果中的重要性.
主要方法:
- 对患者报告的食道疾病结果指标现有文献的综述.
- 对GERD,EoE和achalasia目前的PRO的优缺点进行分析.
- 确定未来PRO开发所需的关键特征.
主要成果:
- 目前针对GERD的PRO通常无法捕捉到全方位的演示文稿,或者以研究为导向.
- 现有的EoE PRO通常是为临床试验而设计的,缺乏全面的症状,内镜和组织学评估.
- 阿卡拉西亚的埃卡德得分有心理测量局限性,特别是它侧重于失调症;较新的PRO提供了更细致的评估.
结论:
- 对于良性食道疾病的新型,用户友好的PROs的开发有显著的需求.
- 未来的PRO应该全面评估临床表现,疾病状态,超警和焦虑,以改善临床后续和研究.
- 增强的PRO将改善生活质量评估,并更好地了解症状严重程度调节器.
关键词:
亚喀拉西亚亚喀拉西亚是一个亚洲地区.埃索诺菲尔性食道炎 (eosinophilic esophagitis) 是一种导致食道炎的疾病.胃食道逆流疾病是胃食道逆流疾病.过度警 过度警 过度警患者报告的结果.更多相关视频
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