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Updated: May 15, 2025

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
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不对称的合成N-基乙氨基原衍生物由工程化伊胺降解酶催化

Jinyang Li1,2, Zefei Xu2, Jinhui Feng2

  • 1School of Biotechnology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.

Organic letters
|April 7, 2025
PubMed
概括

一种新型的伊米因还原酶突变体 (IR262-F185E/F229L) 能够实现合性N-基乙基氨基因丹衍生物的高度反选择性合成. 这一突破为高效生产ozanimod中间体提供了一个有前途的途径.

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