环境温度和卵巢过度刺激综合征:一项观察性研究
Lijuan Fan1, Ping Li1, Juanzi Shi1
1Assisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, People's Republic of China.
概括
卵细胞检索后环境温度较高与严重卵巢过度刺激综合征 (OHSS) 的风险增加有关. 在评估患者的OHSS风险时,医疗保健提供者应考虑环境热量.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 环境健康 环境健康
- 临床产科和妇科 临床产科和妇科
背景情况:
- 卵巢过度刺激综合征 (OHSS) 是辅助生殖技术的一个重要并发症.
- 环境因素,如环境温度对OHSS风险的影响尚未完全理解.
研究的目的:
- 调查环境温度与严重至关键OHSS的发生率之间的关联.
- 为了确定环境温度是否影响卵子检索后的活产率.
主要方法:
- 对28397名40岁或更年轻的女性进行了回顾性队列研究,这些女性接受了卵细胞采集.
- 患者根据卵细胞检索后7天的平均环境温度进行分类.
- 主要结局:严重至危急的OHSS;次要结局:活产率.
主要成果:
- 在更高的环境温度下,观察到严重至危急的OHSS发生率增加.
- 在环境温度升高和高达22.1°C的OHSS风险之间发现了显著的关联 (aOR, 1.025).
- 环境温度和活产率之间没有发现显著的关联.
结论:
- 卵细胞检索后环境温度升高与严重至关键OHSS的风险更高有关.
- 临床医生应在温暖时期接受卵细胞检索的患者中对OHSS保持警.
- 环境热暴露是OHSS的潜在可修改的风险因素.
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