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Updated: May 15, 2025

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
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可见光诱导β-CF2H-1,3-enynes的功能丧失,以访问CF2H含有的全碳四元中心

Shu-Jie Chen1, Jin-Hao Lin1, Jia-Ming Wu1

  • 1School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou, 510006, China. ylliu@gzhu.edu.cn.

Organic & biomolecular chemistry
|April 7, 2025
PubMed
概括

研究人员开发了一种新方法,将二甲基 (CF2H) 组添加到化物中. 这种高效的过程使用 [3+2] 循环添加和光化学重组,产生具有高区域选择性的功能化氨酸衍生物.

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Halogenation of Alkenes

Halogenation is the addition of chlorine or bromine across the double bond in an alkene to yield a vicinal dihalide. The reaction occurs in the presence of inert and non-nucleophilic solvents, such as methylene chloride, chloroform, or carbon tetrachloride.
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A bond is formed between two atoms by sharing two electrons. When this bond is broken by supplying sufficient energy, either two electrons can be taken up by one atom forming ions by the cleavage called heterolysis, or the two electrons are shared by two atoms, with one each creating radicals by the cleavage called homolysis.
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