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非正规的T细胞反应与对小鼠和人类结核病的保护有关

Megan K Proulx1, Christine D Wiggins2, Charlotte J Reames1

  • 1Department of Microbiology, University of Massachusetts Chan Medical School, Worcester, MA, USA.

The Journal of experimental medicine
|April 7, 2025
PubMed
概括

结核菌菌菌 (Mtb) 控制可以在没有高干扰素 (IFNγ) 水平的情况下发生,利用替代的T细胞反应. 这项研究确定了非Th1免疫特征,如Th17细胞,对于小鼠和人类的Mtb耐药性至关重要.

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