五年iStent注射植入的结果,在眼睛中具有开放角玻璃眼球瘤的眼睛中具有或没有发酵化
Ricardo Augusto Paletta Guedes1,2, Daniela Marcelo Gravina3,4, Vanessa Maria Paletta Guedes4
1Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil. palettaguedes@yahoo.com.
Ophthalmology and therapy
|April 7, 2025
概括
第二代带微绕道植入 (iStent注射®) 显著降低了眼内压力和药物负担在开放角度眼光病患者. 这种微创性玻璃眼外科手术 (MIGS) 程序在平均40个月的随访期间表现出持续的有效性.
科学领域:
- 眼科医生 眼科 眼科
- 视光眼管理 视光眼管理
- 手术创新 在外科创新.
背景情况:
- 最少侵入性玻璃眼外科手术 (MIGS) 越来越多地用于开角玻璃眼 (OAG).
- 将MIGS与白内障手术相结合,显示了比单独的白内障手术更大的眼内压 (IOP) 降低.
- 第二代带微绕道植入 (iStent inject®) 为OAG提供了一个潜在的干预方法.
研究的目的:
- 评估iStent inject®在OAG中的长期有效性和安全性.
- 为了比较iStent inject®与白内障手术相结合的结果,而不是作为单独的手术.
- 评估iStent inject®对IOP和局部药物要求的影响.
主要方法:
- 回顾271个眼睛的病例系列,其中有轻度至中度OAG,正在接受iStent注射®植入 (2018-2024年).
- 患者接受了iStent注射®,有或没有发泡乳化 (白内障手术).
- 分析的结果包括40个月的平均随访期间的平均内血压和药物使用.
主要成果:
- 整体平均内血压从16.4 mmHg降至13.7 mmHg (p=0.001).
- 平均药物使用量从2.24下降到0.62 (p=0.001).
- 在组合和独立子组以及轻度/中度OAG组中观察到显著的IOP和药物减少.
结论:
- 随着或没有白内障手术的iStent inject®植入,在OAG中提供了显著和持续的IOP降低.
- 该程序有效地减少了轻度至中度OAG患者的局部药物负担.
- 现实世界的数据支持这种MIGS方法的长期有效性.
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