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Updated: May 15, 2025

Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
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无监督机器学习在纵向队列 (2008-2018) 中识别了阿片类药物缓和逆转模式

Monika Ray1,2, Joshua J Fenton2,3, Patrick S Romano1,2

  • 1Department of Internal Medicine, School of Medicine, University of California Davis, Davis, California, United States of America.

PLOS digital health
|April 7, 2025
PubMed
概括

在慢性疼痛患者中,快速降低阿片类药物剂量可能会增加不良事件. 无监督的人工智能识别了10个患者集群,其缩减速度各不相同,揭示了更快的缩减速度,特别是零度,与更多不良事件和死亡相关.

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