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Updated: May 15, 2025

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients
13:21

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients

Published on: June 16, 2017

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葡萄糖溶解诱导异常转录通过T系急性淋巴细胞白血病的希斯乳酸化

Wenyan Wu1, Jingyi Zhang2, Huiying Sun1

  • 1Key Laboratory of Pediatric Hematology & Oncology Ministry of Health, Department of Hematology & Oncology, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

Genomics, proteomics & bioinformatics
|April 7, 2025
PubMed
概括

乳酸盐通过改变T-ALL.中的基因表征标记,如基因组母乳化 (H3K18la) 来促进癌症. 这种代谢转变驱动白血病发生并影响基因转录,影响患者的预后.

关键词:
希斯 H3 氨酸 18 乳酸化代谢表观遗传相互作用儿科T细胞急性淋巴细胞白血病转录失调的失调是转录失调.华堡效应是什么? 华堡效应

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