相关实验视频
Updated: May 15, 2025

10:42
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
Published on: February 27, 2019
9.3K
专注于治疗性和它们的输送
1Axoltis Pharma, 60 Avenue Rockfeller 69008 Lyon, France; Universite Claude Bernard Lyon 1, CNRS UMR5306, ILM, 2 rue Victor Grignard, 69100 Villeurbanne, France; Universite Claude Bernard Lyon 1, CNRS UMR5007, LAGEPP, 43 boulevard du 11 novembre 1918, Bâtiment CPE 69622 Villeurbanne Cedex, France.
International journal of pharmaceutics
|April 7, 2025
概括
治疗性可以为各种疾病提供精确,安全和有效的治疗方法. 本综述比较了施用途径和输送系统,以优化类药物的疗效和患者的治疗结果.
科学领域:
- 生物化学和药理学 生物化学和药理学
- 药物输送系统 药物输送系统
背景情况:
- 类是通用的治疗剂,可以跨越小分子和大型生物制剂.
- 它们通过更简单的制造提供了增强的特异性,安全性和组织透性.
- 全球治疗药物市场正在迅速扩大,近年来获得了大量批准.
研究的目的:
- 为了比较治疗性的主要亲肠道注射途径 (皮下和静脉注射).
- 分析这些途径对药理动力学概况和患者治疗结果的影响.
- 探索创新的药物递送系统,解决稳定性,生物可用性和疗效方面的挑战.
主要方法:
- 对治疗性的皮下和静脉注射进行比较分析.
- 对药理动力学数据和与不同给药途径相关的患者结局的审查.
- 探索用于类治疗的新型药物递送技术.
主要成果:
- 亲肠道给药途径显著影响的药动力学概况和治疗效果.
- 每种途径都有不同的优势和局限性,影响临床应用.
- 创新的输送系统在克服与稳定性和生物可用性相关的挑战方面表现有前途.
结论:
- 优化的注射路径和输送系统对于最大化治疗效益至关重要.
- 对先进配方的进一步研究可以提高基于的药物的临床实用性.
- 类疗法在现代医学中代表着一个不断增长和重要的领域.
相关概念视频
Drug Delivery: Miscellaneous Routes
282
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
282
Drug Delivery: Parenteral Route
337
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
337
Drug Delivery: Overview
259
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
259

