炎症标志物和预后之间的关系,在通过内血管干预治疗破裂动脉瘤的患者
1Department of Neurosurgery, Gaziantep University, Faculty of Medicine, Gaziantep, Turkiye.
Journal of cerebrovascular and endovascular neurosurgery
|April 7, 2025
概括
炎症标志物,如白细胞计数和C-反应蛋白,预测了前部通讯动脉动脉瘤下关节出血患者的结果,这些患者接受了内血管治疗.
科学领域:
- 神经学 神经学
- 干预性神经辐射学
- 关键护理医学 关键护理医学
背景情况:
- 从前侧通讯动脉 (Acom) 动脉瘤引起的脑下关节下出血 (SAH) 带来了显著的预后挑战.
- 血管内治疗是Acom动脉瘤的主要治疗方法.
- 炎症标志物在预测内血管SAH治疗后的结果中的作用需要进一步阐明.
研究的目的:
- 研究Acom动脉动脉瘤破裂患者手术前炎症标志物的预后价值,通过内血管方法治疗.
- 评估特定的炎症标志物与神经结果之间的相关性.
主要方法:
- 对223名内血管治疗Acom动脉瘤SAH的患者进行了回顾性分析.
- 包括符合特定标准的80名患者,但不包括之前经历过微手术或其他动脉瘤位置的患者.
- 在手术前收集和分析白细胞 (WBC),中性粒细胞,淋巴细胞,C反应蛋白 (CRP),中性粒细胞/淋巴细胞比率 (NLR) 和CRP/淋巴细胞比率 (CLR) 的水平.
主要成果:
- 患者根据修改的兰金尺度 (mRS) 评分 (0-2对3-6) 分为两组.
- 与第一组 (mRS 0-2) 相比,第二组 (mRS 3-6) 的白血球,中性粒细胞,淋巴细胞,CRP,NLR和CLR水平显著更高.
结论:
- 手术前的炎症标志物,包括WBC,CRP,NLR和CLR,与内血管治疗Acom动脉瘤SAH的患者的神经预后有关.
- 这些炎症参数在预测治疗后神经缺陷的严重程度方面具有实用性.
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