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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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通过C-反应蛋白介导的痴呆症.

Jia-Ming Tang1, Qing Lu1, Han-Xiao Lin2

  • 1Department of Neurology, the Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, China.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
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PubMed
概括

C-反应蛋白 (CRP) 与痴呆的风险和进展有关. 在健康人群中CRP水平升高可能预测未来的阿尔茨海默病 (AD),这表明它有可能用于早期查.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.在C-反应性蛋白中,C-反应性蛋白是最重要的.这是一种炎症性炎症.轻度的认知障碍 轻度的认知障碍

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科学领域:

  • 神经科学是一个神经科学.
  • 免疫学 免疫学 免疫学
  • 老年学是一门学科.

背景情况:

  • 痴呆症,特别是阿尔茨海默病 (AD),是导致残疾和死亡的主要原因,其特点是记忆力丧失和人格变化.
  • 痴呆症的神经损伤是不可逆转的,目前对痴呆症的治疗方法有限.
  • 炎症反应与认知障碍有关,高C反应蛋白 (CRP) 水平与AD风险增加有关.

研究的目的:

  • 审查C反应蛋白 (CRP) 和不同类型的痴呆症之间的关系.
  • 探索CRP在认知障碍发展中的作用.
  • 评估CRP测试用于早期AD查和进展监测的潜力.

主要方法:

  • 文献综述侧重于研究C反应蛋白 (CRP) 和痴呆症的研究.
  • 对将炎症标志物与认知衰退联系起来的研究进行分析.
  • 评估CRP作为神经退行性疾病的预测因素.

主要成果:

  • 在健康个体中,C-反应蛋白 (CRP) 水平升高与患阿尔茨海默病 (AD) 的可能性增加有关.
  • CRP是已知的神经退行性疾病的风险因素和预测因素.
  • CRP测试是可访问和具有成本效益的,表明其潜在的临床实用性.

结论:

  • C-反应蛋白 (CRP) 在痴呆的发病过程中起着重要作用,包括阿尔茨海默病 (AD).
  • CRP测试为早期发现和监测痴呆症进展提供了一个有希望的,具有成本效益的工具.
  • 对CRP在认知障碍中的机制的进一步研究可能会导致新的治疗策略.