思想重要:焦虑和抑郁如何塑造低风险的前列腺癌在现实世界人口中的积极监测遵守
Zachariah Taylor1, Kayla Meyer2, Danielle Terrenzio2
1Main Line Health System, Wynnewood, PA 19096, USA.
The Canadian journal of urology
|April 7, 2025
概括
患有焦虑或抑郁症的男性不太可能接受低风险前列腺癌的积极监测. 他们也有更高的选择立即治疗而不是监测的比率.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 前列腺癌的诊断影响心理健康.
- 积极监测是低风险前列腺癌的常见管理策略.
- 预先存在的焦虑/抑郁症对积极监测遵守的影响尚不清楚.
研究的目的:
- 评估先前焦虑和/或抑郁之间的关联,以及遵守积极监测协议.
- 研究心理健康对低风险前列腺癌患者治疗决策的影响.
主要方法:
- 对426名患有低风险前列腺癌的男性进行了回顾性多中心研究.
- 通过PSA测试和活检完成在18个月内定义的积极监测遵守.
- 过早治疗被定义为终极治疗 (辐射或前列腺切除术).
主要成果:
- 患有先前精神健康诊断的患者对积极监测的坚持明显较低 (27.6%与49.5%相比).
- 这些患者对PSA检测和活检的坚持减少,并且更有可能选择立即治疗 (39.7%与25.0%相比).
- 在单个和联合焦虑和抑郁症诊断的患者之间,没有发现坚持的显著差异.
结论:
- 预先存在的焦虑和/或抑郁症与低风险前列腺癌中积极监测的遵守程度降低有关.
- 心理健康状况影响治疗选择,可能导致过早治疗.
- 解决精神因素对于在积极监测下低风险前列腺癌患者的有效管理至关重要.
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