没有常规抗生素的前列腺外皮活检表明感染风险降低
Benjamin J Lichtbroun1,2, Mann Patel2, Alexis Consalvo2
1Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ 08901, USA.
The Canadian journal of urology
|April 7, 2025
概括
与跨直肠活检相比,跨关前列腺活检显著减少了传染性并发症. 这种方法可以在没有常规抗生素或肠道准备的情况下安全地进行,解决抗生素耐药性的问题.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 外科手术的安全性
背景情况:
- 与前列腺活检相关的感染是一个重大问题,因抗生素耐药性增加而加剧.
- 跨直肠前列腺活检传统上涉及外科手术期间的抗生素和肠道准备,以减轻感染风险.
研究的目的:
- 为了比较跨腹膜与跨直肠前列腺活检技术的安全结果.
- 为了评估传染性并发症,急诊室访问和30天的再入院,用于两种活检方法.
主要方法:
- 在2019-2022年期间,对319名患者进行了跨直肠 (n=174) 或跨关节 (n=145) 前列腺活检的回顾性分析.
- 两组之间的抗生素使用,肠道准备率和手术后不良事件的比较.
主要成果:
- 经膜活检患者的感染并发症为零,而经膜活检组的感染并发症为5.17% (p=0.005).
- 紧急病房访问 (4.60%对0%,p=0.036) 和30天的再入院 (4.02%对0%,p=0.015) 在跨关节组显著下降.
- 只有5.5%的透患者接受了抗生素,35.86%接受了肠道制备剂,而跨直肠组的两种患者的比例为100%.
结论:
- 跨关前列腺活检显示出优越的安全性,感染并发症明显少于跨直肠活检.
- 经关节的方法可以安全地使用最小的或没有经手术期间的抗生素和肠道准备.
- 这种技术提供了一种可行的替代方案,以减少与医疗保健相关的感染,并在前列腺活检过程中打击抗生素耐药性.
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