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Updated: May 23, 2025

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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胚胎干细胞中转录因子的异质凝聚物:分子模拟

Azuki Mizutani1, Cheng Tan2, Yuji Sugita3

  • 1Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.

Biophysical journal
|April 8, 2025
PubMed
概括

干细胞中的转录因子凝结物是复杂的. Klf4充当了支架,Sox2和Nanog稳定了它,而Oct4是客户端,揭示了异质生物分子组件中的关键相互作用.

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