一个COSMIN系统审查瑞士患者报告的通用结果措施
Thanh Elsener1,2, Matthew Kerry3, Nikola Biller-Andorno4
1Institute of Public Health, ZHAW Zurich University of Applied Sciences, Katharina-Sulzer-Platz 9, Winterthur, 8400, Zurich, Switzerland. else@zhaw.ch.
概括
本系统性审查评估了瑞士患者报告的结果措施 (PROMs). 建议使用SF-36,而EQ-5D不适合未来使用.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 医疗信息学 医疗信息学
- 心理测量 心理测量 心理测量
背景情况:
- 患者报告的结果指标 (PROM) 对于在临床实践,研究和人口研究中评估健康状况至关重要.
- 选择合适的通用PROM对于可靠和有效的健康结果评估至关重要.
- 瑞士需要关于在医疗保健中最佳使用仿制PROM的指导.
研究的目的:
- 系统地审查瑞士使用的通用PROM的质量.
- 应用基于共识的健康测量仪器选择标准 (COSMIN) 方法来进行质量评估.
- 为瑞士使用通用PROM提供基于证据的建议.
主要方法:
- 在六个数据库和瑞士灰色文献中进行了全面的搜索,发现了关于通用PROM开发或验证的研究.
- 在COSMIN偏差风险检查清单中评估了方法质量.
- 测量属性 (内容有效性,心理测量) 根据COSMIN标准进行评估.
- 综合证据使用了修改后的GRADE方法来制定建议.
主要成果:
- 49项研究报告了五种通用PROMs:EQ-5D,SF-36,PROMIS-29,WHOQOL-BREF和WORQ. 这三种类型的PROM.
- SF-36显示出足够的质量,并建议使用.
- PROMIS-29,WHOQOL-BREF和WORQ显示出潜力,但需要进一步验证.
- 不建议在未来在瑞士使用EQ-5D.
结论:
- 根据综合证据,SF-36是目前在瑞士使用的唯一可推的通用PROM.
- 通过额外的验证研究,PROMIS-29,WHOQOL-BREF和WORQ可能会成为可推的.
- EQ-5D被认为不适合在瑞士医疗保健环境中未来应用.
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