对双门内镜脊柱手术与体内融合进行系统审查
Wongthawat Liawrungrueang1, Ho-Jin Lee2, Sang Bum Kim2
1Department of Orthopaedics, School of Medicine, University of Phayao, Phayao, Thailand.
Asian spine journal
|April 8, 2025
概括
双门内镜脊柱手术 (BESS) 与体内融合为腰部退行性疾病提供了很好的结果,显示出高的融合率和最小的并发症. 需要进一步的研究来证实它在复杂病例中的长期有效性.
科学领域:
- 神经外科 神经外科
- 整形外科手术 整形外科手术
- 最少侵入性的脊柱手术
背景情况:
- 双门内镜脊柱手术 (BESS) 与体内融合是腰部退行性疾病的新兴技术.
- 它旨在尽量减少组织创伤,血液损失和恢复时间,同时保持临床疗效.
- 目前缺乏对BESS有效性,并发症和长期结果的全面分析.
研究的目的:
- 系统地审查临床结果,手术疗效和BESS的并发症率与腰部退行性疾病的体内融合.
- 提供BESS的比较分析,突出其优势,局限性和微创脊柱手术中的新兴趋势.
- 综合现有证据,以指导未来的研究和临床应用.
主要方法:
- 使用MeSH术语和关键词对PubMed/Medline和Scopus数据库进行系统的文献搜索 (2000年1月至2024年9月).
- 包括12项评估临床结果,手术时间,血液损失,融合率和并发症的研究.
- 使用ROBINS-I工具评估的偏差风险.
主要成果:
- 平均操作时间从98到206分钟不等;融合率在70%到95%之间.
- 观察到视觉模拟量表 (VAS) 疼痛和奥斯威斯特残疾指数 (ODI) 评分的显著改善.
- 诸如持续性撕裂 (2.9%-6.4%) 和血液瘤 (1.4%-4.3%) 等并发症并不常见.
结论:
- 使用体内融合的BESS显示出出色的临床结果,高的融合率,以及腰部退行性疾病的低并发症概况.
- 这项技术在微创脊柱手术方面表现有前途.
- 需要进一步的随机对照试验和长期研究来验证更广泛的适用性,特别是在复杂或多层次的脊柱病理中.
相关概念视频
03:08Hydroboration-Oxidation of Alkenes
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
02:15Preparation of Alcohols via Addition Reactions
Overview
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
02:35Acid-Catalyzed Dehydration of Alcohols to Alkenes
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02:37Oxidation of Alcohols
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The process of oxidation in a chemical reaction is observed in any of the three forms:
The process of oxidation in a chemical reaction is observed in any of the three forms:
01:33Preparation of Aldehydes and Ketones from Alcohols, Alkenes, and Alkynes
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The carbonyl center is activated by...
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