视网膜静脉封闭的危险因素在东亚:一个元分析
Xinyue Qiu1,2, Ziman Jiao1,2, Yuxin Liu1,2
1Department of Ophthalmology, Affiliated People's Hospital (Fujian Provincial People's Hospital), Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Frontiers in ophthalmology
|April 8, 2025
概括
这一元分析确定了东亚人群中视网膜静脉封闭 (RVO) 的关键风险因素. 慢性病,高血压,高脂血症和糖尿病显著增加RVO风险.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 视网膜静脉封闭 (RVO) 对视力构成重大威胁,特别是在东亚人群中.
- 了解区域风险因素对于制定有针对性的预防和控制战略至关重要.
研究的目的:
- 进行元分析,评估与东亚人口中RVO相关的风险因素.
- 在这个人口群体中为RVO提供有针对性的控制策略.
主要方法:
- 在多个数据库 (PubMed, Web of Science, Cochrane Library, CNKI, Wanfang, VIP) 进行了系统的文献搜索,直到2024年5月.
- 通过纽卡斯尔-太华量表 (NOS) 评估研究的质量.
- 使用Review Manager软件对21项纳入研究中提取的数据进行了元分析.
主要成果:
- 分析包括27,561例RVO病例和514,578例对照病例.
- 确定RVO的重要危险因素包括慢性病 (OR=4.14),高血压 (OR=4.11),高脂血症 (OR=3.45),以及糖尿病 (OR=3.00).
- 升高的同类半氨酸水平显示出非显著的关联趋势 (OR=0.87).
结论:
- RVO的发生与慢性病,高血压,高脂血症,糖尿病和高水平的同类氨酸密切相关.
- 临床医生应在RVO的诊断和治疗中优先考虑对这些风险因素的查和管理.
- 针对这些可修改的风险因素的有针对性的干预措施可以帮助在东亚人口中预防RVO.
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