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在全心室放射治疗后,过渡性视网膜血管美白

Takahiro Kogo¹, Yuki Muraoka¹, Hirohito Kubota²

¹Ophthalmology and Visual Sciences, Kyoto University, Kyoto, JPN.

|April 8, 2025

概括

在放射治疗后的一名儿科患者中,视网膜血管的短暂变白自发地消失. 这种可逆的非缺血性变化凸显了在低剂量辐射的情况下视网膜评估的重要性.

科学领域:

眼科医生眼科眼科
辐射瘤学辐射瘤学
儿科瘤学儿科瘤学

背景情况:

辐射视网膜病变是放射治疗的已知并发症,通常发生在较高剂量时.
为中枢神经系统或垂体瘤接受放射治疗的儿科患者可能面临眼部副作用的风险.
了解辐射诱导的眼部变化的频谱对于患者管理至关重要.

研究的目的:

在全心室放射治疗后的儿科患者中报告一个暂时的外周视网膜血管变白的病例.
用先进的成像技术来调查这种视网膜变化的性质.
讨论对儿童患者辐射诱导的眼睛效应的查和管理的影响.

主要方法:

一个11岁的女孩患有下垂体胚芽瘤的病例报告.
治疗包括化疗和全心室放射治疗 (23.4 Gy).
使用超广场扫描激光眼镜和光学连贯性断层扫描血管学 (OCTA) 的眼科评估.

主要成果:

在放射治疗后两个月观察到双边外周视网膜血管白化.
OCTA证实保留了视网膜血流,排除了缺血.
视网膜白化在两个月内自发消失,没有任何干预.

结论:

暂时的,非缺血的外周视网膜血管变白可能发生在比通常与辐射视网膜病变相关的辐射剂量低的辐射剂量下.
这一可逆的发现可能与年轻患者的血管可塑性有关.
强调即使在低剂量照射下也需要进行视网膜评估,以及OCTA在监测微妙变化的有用性.

关键词:

光学连贯性断层扫描血管图谱辐射视网膜病变辐射视网膜病变视网膜血管白化视网膜血管白化超广场扫描激光眼镜镜眼镜镜.全心室辐射疗法

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