一个直肠膜血瘤的病例是由于自行注射 Certolizumab Pegol而引起的
Atsuhiko Suenaga1, Yuka Hashimoto2, Akiko Kanaya3
1Department of Nephrology, National Hospital Organization Ureshino Medical Center, Ureshino, JPN.
Cureus
|April 8, 2025
概括
这份病例报告详细介绍了使用Certolizumab pegol的患者的直肠血瘤 (RSH). 它强调了RSH的潜在风险因素,包括药物使用和患者的并发症.
科学领域:
- 胃肠病学和肝病学
- 放射学和成像学 放射学和成像学
- 类风湿病学 类风湿病学
背景情况:
- 直肠血瘤 (RSH) 是一种临床疾病,涉及直肠腹肌内出血.
- 它可以表现为腹痛,并与腹壁脂肪低,自动注射器使用和抗凝剂治疗等因素有关,特别是在末期功能衰竭和类风湿性关节炎患者中.
研究的目的:
- 报告与克尔科利祖马布佩戈尔注射相关的直肠血瘤 (RSH) 的第一个病例.
- 讨论在这个特定患者群体中可能导致RSH的潜在因素.
主要方法:
- 一个61岁的男性患者的案例研究,患有末期功能衰竭和类风湿性关节炎,出现腹痛.
- 使用计算机断层扫描 (CT) 进行诊断成像,以识别直肠血瘤.
- 干预性放射学手术,涉及由于疼痛升级而导致左下腹上动脉 (IEA) 的跨导管动脉栓塞 (TAE).
主要成果:
- 计算机断层扫描证实了一个大,高密度的左侧直肠膜血瘤.
- 通过导管动脉栓塞成功地进行了管理不断升级的腹痛.
- 这代表了首次记录的RSH与certollizumab pegol管理相关的案例.
结论:
- 塞尔科利祖马布佩戈尔 ( Certolizumab pegol),特别是当自己注射到腹壁时,可能是直肠血瘤的新奇原因.
- 临床医生应考虑在患有相关并发症 (末期功能衰竭,类风湿性关节炎) 和腹壁注射的患者中进行RSH,特别是在使用自动注射器设备时.
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