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综合生物信息学分析和生物实验,以确定血管痴呆症的关键免疫基因

Yilong Zhao1,2, Wen Xing3,4,5,6, Weiqi Chen1,2

  • 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Frontiers in immunology
|April 8, 2025
PubMed
概括

研究人员确定RAC1和CMTM5是血管痴呆症 (VaD) 诊断的关键免疫基因. 这些基因在小鼠模型中表现出改变的表达,为VaD机制和潜在的生物标志物提供了新的见解.

关键词:
在CMTM5中,CMTM5是在RAC1中,RAC1是指RAC1.生物信息学是一种生物信息学.机器学习是机器学习.血管痴呆症是一种精神病.

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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...