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用PANDORA预测MHCII类的逆结合形状

Daniel T Rademaker1,2,3, Farzaneh M Parizi4, Marieke van Vreeswijk3,4

  • 1Biosystems Data Analysis, University of Amsterdam, Amsterdam, Netherlands.

Frontiers in immunology
|April 8, 2025
PubMed
概括

发现揭示可以反向结合主要基因相容性复合体 (MHC) II 类分子,激活T细胞. 潘多拉软件现在模拟了这些反向,推进了免疫疗法和疫苗设计.

关键词:
在 HLA II 的情况下,HLA II在MHC II中,MHC II是最重要的.同源性建模的同源性建模这是一种MHC-MHC.反向结合的酸.

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