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Updated: May 15, 2025

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SETD1A的基因组和转录组签名 破坏人类刺激神经元发育和精神疾病风险

Zhixiong Sun1,2,3, Huixiang Zhu2,3, Xiaofu He2

  • 1Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.

bioRxiv : the preprint server for biology
|April 8, 2025
PubMed
概括

对SETD1A的遗传破坏增加了精神分裂症的风险. 这项研究揭示了SETD1A功能丧失突变如何影响人类大脑发育和基因调节,提供了对精神分裂症病原学的见解.

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