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Updated: May 1, 2026

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow
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Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

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高通量蛋白质标映射可以加速对ToxCast和PFAS化合物的生物活性发现

Diwen Yang1,2, Xiaoyun Wang1, Jiabao Liu1,3

  • 1Department of Chemistry, University of Toronto, Toronto, ON, Canada.

bioRxiv : the preprint server for biology
|April 8, 2025
PubMed
概括

这项研究使用质谱法来发现化学污染物的新蛋白质标. 脂肪酸结合蛋白 (FABPs) 结合到和多基基物质 (PFAS),而新的PFAS显示了更广泛的结合.

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Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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