电子健康干预对接受脏移植患者药物坚持的影响:随机对照试验的元分析
Metin Tuncer1, Gülsüm Zekiye Tuncer2
1Department of Nursing Fundamentals, Gümüşhane University, Gümüşhane, Türkiye.
Journal of renal care
|April 8, 2025
概括
电子健康 (eHealth) 干预措施显著改善了移植患者的药物坚持. 这些数字工具提供了一个有希望的策略,以提高长期的移植存活率和患者的结果.
科学领域:
- 腎病學和移植科
- 数字健康和医疗信息学
- 药理学和治疗学 药理学和治疗学
背景情况:
- 接受移植的接受者需要终身免疫抑制,这使得药物坚持对于移植的生存至关重要.
- 免疫抑制剂的不坚持是移植患者移植损失和死亡的主要原因之一.
- 电子健康应用程序为改善慢性疾病管理提供了技术解决方案,包括药物坚持.
研究的目的:
- 评估电子卫生干预措施在提高移植接受者药物服药的有效性.
- 这一元分析综合了随机对照试验 (RCT) 的发现,以评估电子健康的影响.
主要方法:
- 一个系统的审查和元分析,遵循PRISMA指南.
- 搜索电子数据库 (PubMed,Medline,科学网,Scopus) 并对RCT进行手动文献搜索.
- 包括在2014年至2024年3月期间发表的8项与779名参与者的RCT.
主要成果:
- 与标准护理相比,电子健康干预导致了显著更高的坚持率 (RR: 1.19; p=0.01).
- 电子健康小组的参与者表现出改善的药物坚持得分 (SMD:0.17;p=0.02).
- 在包括的研究中观察到很低的异质性 (I2=19%的率,I2=0%的得分).
结论:
- 电子健康干预措施在改善移植患者的药物守方面表现出有利的结果.
- 这些干预措施被推用于提高长期存活率和移植后的整体患者结果.
- 数字健康工具在管理移植患者时,为标准护理提供了有价值的补充.
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