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跨支气管中结肠透视诊断产量和外科手术期间的患者管理:一个单一的三级中心经验

Nadia Corcione¹, Alfonso Pecoraro¹, Andrea Fidecicchi²

¹Interventional Pulmonology Unit, Department of Pulmonology, Oncology and Hematology, Antonio Cardarelli Hospital, Naples, Italy.

Thoracic research and practice

|April 8, 2025

概括

与EBUS-TBNA相比,内支气管超声波导向的横支气管中冷活检 (TMC) 显著改善了血液学疾病,良性肺部疾病和不常见瘤的诊断产量. TMC表现出优异的耐受性和可比的结果,用于原发性肺癌分子分析.

科学领域:

肺部病理学肺部病理学
干预性肺病学干预性肺病学
诊断性支气管镜检查支气管镜检查

背景情况:

胸腔内膜超声导向的跨支气管针吸收 (EBUS-TBNA) 是中病变诊断的标准.
小型EBUS-TBNA样本可能不足以诊断良性肺部疾病,血液学疾病和原发性肺癌 (PLC) 的分子分析.
内支气管超声波导向的横支气管中支气管冷活检 (TMC) 产生组织样本,可能提供更高的诊断产量 (DY).

研究的目的:

批判性地分析TMC的诊断产量 (DY) 和术后管理.
为了比较TMC与EBUS-TBNA的临床影响.

主要方法:

一个单一中心的回顾性研究评估了TMC超过11个月 (2023年2月至2024年1月).
包括的患者接受了TMC以诊断中骨病变.
分析了诊断产量和术后患者管理的数据.

主要成果:

TMC的整体DY为95.1%,明显高于EBUS-TBNA的41.5%.
在血液学疾病,良性疾病和不常见瘤方面,TMC显示出优异的DY (100%对比31%).
对于PLC,DY和免疫组织化学标记的评估在TMC和EBUS-TBNA之间是相似的 (100%与80%对比).

结论:

对于特定疾病,如血液学疾病和良性肺部疾病,TMC的诊断产量明显优于EBUS-TBNA.
TMC具有最佳的耐受性概况,没有观察到治疗水平在治疗后的升级.
术后管理,包括抗血栓治疗,可以遵循EBUS-TBNA协议,通常使用深度镇静.

关键词:

支气管镜检查 (bronchoscopy) 是一种用于检查支气管的方法.诊断方法诊断方法胸腔内膜超声波指导的跨胸腔针吸入.肺癌是一种肺癌.中间肠道疾病中间肠道疾病.在外科手术期间的护理.

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