老年人群的体重指数轨迹和全因死亡率:中国的一项队列研究
Xiaodan Kuang1, Liuhong Tian1, Shulei Chen1
1Department of Epidemiology and Health Statistics, School of Public Health, Wenzhou Medical University, University Town, Chashan, Wenzhou, 325035, Zhejiang, China.
BMC public health
|April 8, 2025
概括
在老年人中,稳定的低正常体重指数 (BMI) 轨迹与增加的死亡风险有关. 保持正常的BMI可能对中国老年人长寿至关重要.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 关于身体质量指数 (BMI) 轨迹和老年人死亡率的研究有限,特别是在中国人口中.
- 了解生命晚期的BMI变化对于有针对性的健康干预至关重要.
研究的目的:
- 调查中国老年人BMI轨迹与全因死亡率之间的关联.
- 探索这种关系中的潜在调解因素,如认知功能和生活方式.
主要方法:
- 隐性类增长建模用于从中国纵向健康长寿调查 (2008年,2011年,2014年) 中确定BMI轨迹.
- 考克斯比例危险回归分析了已识别的BMI轨迹与全因死亡率之间的关联,直到2019年7月.
- 进行了调解和值分析,以探索潜在的机制和BMI与死亡率的关系.
主要成果:
- 确定了三个BMI轨迹:稳定的低正常 (47.33%),正常的轻微增加 (44.45%),以及超重到肥胖 (8.22%).
- 与正常轻微增加相比,稳定的低正常BMI轨迹显著增加了全因死亡风险 (HR=1.39).
- 认知障碍和休活动减少可能部分调解这种关联;死亡风险降低,BMI高达26kg/m2.
结论:
- 在老年人中,稳定的低正常BMI轨迹与所有原因死亡的风险更高有关.
- 这些发现强调了监测老年人BMI轨迹的重要性,以制定有效的健康管理策略.
- 干预措施应侧重于维持健康的BMI范围,以改善老年人的健康状况和生活质量.
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